genomic stability
[/dʒɪˈnɒmɪk stəˈbɪlɪti/]
nounfeminine
estabilidade genômica
1. The ability of a genome to maintain its integrity and resist changes or damage to its DNA sequence during cell division and throughout an organism's lifetime
Genomic stability is crucial for preventing mutations that could lead to cancer development.
A estabilidade genômica é crucial para prevenir mutações que poderiam levar ao desenvolvimento do câncer.
2. The preservation of chromosomal structure and genetic information without unwanted alterations or rearrangements
Researchers study genomic stability to understand aging and disease mechanisms.
Os pesquisadores estudam a estabilidade genômica para entender os mecanismos de envelhecimento e doença.
3. The cellular mechanisms and processes that protect DNA from damage and ensure accurate replication
Genomic stability depends on efficient DNA repair mechanisms and checkpoint controls.
A estabilidade genômica depende de mecanismos eficientes de reparo de DNA e controles de checkpoint.
This term is primarily used in scientific and medical contexts in both Brazil and the USA. It is fundamental in molecular biology, genetics, and oncology research. In Brazil, this terminology is standard in university research programs and medical literature, particularly in cancer research and genetic studies. The term reflects the international scientific community's focus on understanding cellular mechanisms that prevent disease.
Related Idioms & Phrases
maintain genomic stability
compromise genomic stability
genomic stability is compromised
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