DNA damage

[/ˌdiːɛnˈeɪ ˈdæmɪdʒ/]
nounpl: DNA damages
dano ao DNA
1. Physical or chemical alteration of DNA molecules that impairs their normal function, caused by environmental factors, radiation, chemicals, or errors in replication
DNA damage from UV radiation can lead to skin cancer if not properly repaired.
O dano ao DNA causado pela radiação UV pode levar ao câncer de pele se não for adequadamente reparado.
2. Lesions or breaks in the DNA double helix structure that compromise genetic information integrity
The cells have mechanisms to detect and repair DNA damage before it becomes permanent.
As células possuem mecanismos para detectar e reparar o dano ao DNA antes que se torne permanente.
This is a specialized scientific and medical term used primarily in academic, research, and clinical settings in both Brazil and the USA. It has gained prominence in public discourse with discussions about cancer prevention, aging, and environmental health. The term is consistent across English-speaking countries and Portuguese-speaking regions, reflecting its scientific standardization.
Synonyms / Sinônimos
genetic damagechromosomal damageDNA lesionnucleotide alteration
Antonyms / Antônimos
DNA repairgenetic integritygenomic stability

Regional Variations

General Brazilian Portuguese
dano ao DNA
Standard scientific term used across Brazil
São Paulo
dano ao DNA / lesão no DNA
Both terms commonly used in research institutions
Rio de Janeiro
dano ao DNA
Standard usage in medical and scientific contexts
Portugal
dano no DNA / lesão do DNA
European Portuguese may prefer 'no' over 'ao'; also uses 'lesão'

Related Words

DNA repair mechanismsmutationcarcinogenesisapoptosisgenomic stabilitymutagenesis

Related Idioms & Phrases

DNA damage accumulation
oxidative DNA damage
UV-induced DNA damage
genotoxic DNA damage
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