chromosomal damage

[kroh-muh-SOH-muhl DAM-ij]
nounpl: chromosomal damages
dano cromossômico
1. Physical or chemical injury to chromosomes that results in breakage, loss, rearrangement, or alteration of genetic material, potentially causing mutations or cell dysfunction
Exposure to radiation can cause chromosomal damage that may lead to genetic disorders in offspring.
A exposição à radiação pode causar dano cromossômico que pode levar a transtornos genéticos na descendência.
2. Structural aberrations in chromosomes including deletions, duplications, inversions, and translocations visible through microscopic analysis
The laboratory detected chromosomal damage in the patient's white blood cells.
O laboratório detectou dano cromossômico nas células brancas do sangue do paciente.
This term is primarily used in medical, scientific, and genetic counseling contexts in both Brazil and the USA. In Brazil, it appears frequently in genetics research and clinical diagnostics. The term has gained importance in discussions of environmental health and occupational safety, particularly regarding exposure to mutagens and carcinogens.
Synonyms / Sinônimos
chromosomal abnormalitychromosomal aberrationgenetic damageDNA damagechromosomal injury
Antonyms / Antônimos
chromosomal integritygenetic stability

Regional Variations

General Brazilian
dano cromossômico
Standard medical terminology used throughout Brazil
Rio de Janeiro
dano cromossômico
Same as general usage
São Paulo
dano cromossômico
Common in medical and scientific research contexts
Portugal
dano cromossómico
European Portuguese spelling with accent variation

Related Words

mutationgenetic disorderkaryotypeaneuploidytranslocationdeletionduplicationcytogenetics

Related Idioms & Phrases

chromosomal damage at the cellular level
repair of chromosomal damage
assess chromosomal damage
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