cell cycle checkpoint
[sel ˈsaɪkəl ˈtʃɛkpɔɪnt]
nounpl: cell cycle checkpoints
ponto de controle do ciclo celular
1. A regulatory mechanism in the cell cycle that monitors cellular conditions and prevents progression to the next phase if conditions are not appropriate, ensuring genome integrity and proper cell division
The G1/S checkpoint prevents cells from entering S phase if DNA damage is detected.
O ponto de controle G1/S impede que as células entrem na fase S se dano no DNA for detectado.
2. A control point where the cell evaluates whether it can safely proceed with DNA replication or mitosis
Cancer cells often bypass cell cycle checkpoints, leading to uncontrolled division.
Células cancerígenas frequentemente contornam os pontos de controle do ciclo celular, levando à divisão descontrolada.
This is primarily a scientific and medical terminology used uniformly across both Brazil and Portugal in academic and healthcare settings. The term is fundamental in cell biology education and cancer research discussions, with minimal regional variation in usage.
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