DNA instability
[/ˌdiː ɛn ˈeɪ ɪnstəˈbɪləti/]
nounpl: DNA instabilities
instabilidade do DNA
1. A condition characterized by the abnormal alteration, rearrangement, or degradation of DNA sequences, leading to genetic mutations and chromosomal abnormalities
DNA instability in cancer cells often results from defective repair mechanisms.
A instabilidade do DNA em células cancerosas frequentemente resulta de mecanismos de reparo defeituosos.
2. The propensity of genetic material to undergo spontaneous changes or breakage during replication or under cellular stress
Researchers studied DNA instability induced by radiation exposure.
Os pesquisadores estudaram a instabilidade do DNA induzida pela exposição à radiação.
This term is primarily used in scientific, medical, and academic contexts in both Brazil and the USA. It is a technical term essential in oncology, genetics, and molecular biology research. The concept is particularly significant in cancer research where DNA instability is a hallmark of malignant transformations.
Related Idioms & Phrases
genetic time bomb (figurative reference to DNA instability leading to disease)
rogue genes (informal reference to unstable DNA sequences)
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