true cholinesterase
[tro͞o ˌkōlənˈestərāz]
nounpl: true cholinesterases
acetilcolinesterase verdadeira
1. An enzyme (acetylcholinesterase) that catalyzes the hydrolysis of acetylcholine at synapses and neuromuscular junctions, found primarily in red blood cells, nerve tissue, and muscle tissue
True cholinesterase levels in the blood are used as a biomarker for organophosphate pesticide exposure.
Os níveis de acetilcolinesterase verdadeira no sangue são usados como biomarcador de exposição a pesticidas organofosforados.
2. A specific type of cholinesterase enzyme distinct from pseudocholinesterase, with high specificity for acetylcholine substrates
The inhibition of true cholinesterase by nerve agents is the basis for their neurotoxic effects.
A inibição da acetilcolinesterase verdadeira por agentes nervosos é a base para seus efeitos neurotóxicos.
True cholinesterase is a technical term primarily used in medical, toxicological, and biochemical contexts in both Brazil and the USA. It is particularly relevant in occupational health monitoring for workers exposed to pesticides and nerve agents, making it an important term in public health discourse and clinical laboratory practice in both countries.
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