AChE

[ey-see-aytch-ee]
noun
acetilcolinesterase
1. An enzyme that breaks down acetylcholine, a neurotransmitter, in the synaptic cleft and at the neuromuscular junction
AChE inhibitors are used in the treatment of Alzheimer's disease to preserve acetylcholine levels
Inibidores de AChE são usados no tratamento da doença de Alzheimer para preservar os níveis de acetilcolina
2. Acetylcholinesterase; the key enzyme in the cholinergic nervous system responsible for terminating neurotransmission
The activity of AChE is crucial for proper muscle contraction and relaxation
A atividade da AChE é crucial para a contração e relaxamento adequados dos músculos
AChE is primarily used in medical, pharmaceutical, and neuroscience contexts. It is a critical target in pharmacology, particularly for Alzheimer's disease treatments and nerve agent antidotes. The term is used identically in both Brazilian Portuguese and English scientific communities, reflecting the international nature of medical nomenclature.
Synonyms / Sinônimos
acetylcholinesterasecholinesteraseacetyl-CoA hydrolase

Regional Variations

General Brazilian
acetilcolinesterase
Standard medical/scientific terminology used throughout Brazil
Portugal
acetilcolinesterase
Same standard medical terminology as in Brazil
USA
acetylcholinesterase
Standard English abbreviation used in American medical literature

Related Words

acetylcholineneurotransmittercholinergicsynaptic cleftAChE inhibitoranticholinesterase
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