poor affinity
[/pʊr əˈfɪnɪti/]
noun phrasepl: poor affinities
baixa afinidade
1. A weak or limited chemical, biological, or interpersonal connection or attraction between two substances, organisms, or people
The enzyme showed poor affinity for the substrate, resulting in slower reaction rates.
A enzima mostrou baixa afinidade pelo substrato, resultando em taxas de reação mais lentas.
2. In biochemistry, a condition where a receptor has difficulty binding to its ligand with high strength
The drug demonstrated poor affinity for cancer cells, limiting its therapeutic effectiveness.
O fármaco demonstrou baixa afinidade pelas células cancerosas, limitando sua eficácia terapêutica.
3. A lack of natural compatibility or connection between people or groups
Despite working together for years, they had poor affinity and rarely collaborated on projects.
Apesar de trabalharem juntos por anos, eles tinham baixa afinidade e raramente colaboravam em projetos.
This term is predominantly used in scientific, medical, and biochemical contexts in both Brazilian Portuguese and American English. It is rarely used in casual conversation. In Brazil, it is frequently encountered in pharmaceutical research, molecular biology textbooks, and clinical settings. The concept is essential to understanding drug development and efficacy in both cultures.
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