native nucleoside
[ˈneɪtɪv ˈnjuːkliəsaɪd]
nounpl: native nucleosides
nucleosídeo nativo
1. A nucleoside that occurs naturally in living organisms, composed of a nitrogenous base covalently bonded to a five-carbon sugar (ribose or deoxyribose), without a phosphate group
Adenosine is a native nucleoside found in all cells.
A adenosina é um nucleosídeo nativo encontrado em todas as células.
2. In molecular biology, a naturally occurring building block of nucleic acids that has not been chemically modified or synthesized in a laboratory
Native nucleosides serve as substrates for nucleotidyltransferases in DNA synthesis.
Os nucleosídeos nativos servem como substratos para nucleotidiltransferases na síntese de DNA.
This is a specialized scientific term used primarily in molecular biology, biochemistry, and pharmaceutical research contexts. It is not commonly used in everyday conversation in either Brazil or the USA, but is standard terminology in academic and professional laboratory settings. The distinction between native and modified nucleosides is particularly important in drug development and synthetic biology research.
Related Idioms & Phrases
native nucleoside pool - the collection of naturally occurring nucleosides available in a cell
native nucleoside incorporation - the process by which natural nucleosides are added to growing DNA or RNA chains
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