1. Third person singular present indicative of 'estar' (to be) + adjective 'confortável' (comfortable). Describes a state of physical or mental comfort.
Is he comfortable in that chair?
Ele está confortável naquela cadeira?
2. Indicates that someone feels at ease, relaxed, or without discomfort in a situation or location.
She is comfortable with the decision.
Ela está confortável com a decisão.