altered nucleoside
[/ˈɔːltərd ˈnjuːkliəsaɪd/]
nounpl: altered nucleosides
nucleosídeo alterado
1. A nucleoside that has undergone chemical modification from its standard form, with changes to the nitrogenous base, sugar component, or both, often occurring naturally or induced artificially
Pseudouridine is an altered nucleoside commonly found in transfer RNA molecules.
A pseudouridina é um nucleosídeo alterado comumente encontrado em moléculas de RNA de transferência.
2. A modified nucleoside used in research, diagnostics, or therapeutic applications to study or interfere with nucleic acid function
Researchers used altered nucleosides to track DNA replication in the cell nucleus.
Os pesquisadores usaram nucleosídeos alterados para rastrear a replicação de DNA no núcleo celular.
This is technical scientific terminology primarily used in biochemistry, molecular biology, and pharmaceutical research contexts in both Brazil and the United States. The term is not subject to regional variation in meaning and is used consistently across English and Portuguese-speaking scientific communities.
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