1. A situation, environment, or circumstance that is unfavorable, hostile, or challenging; conditions that work against success or well-being
The company managed to maintain profitability despite an adverse setting marked by economic recession and increased competition.
A empresa conseguiu manter a lucratividade apesar de um contexto adverso marcado por recessão econômica e aumento da concorrência.
2. In legal or clinical contexts, unfavorable conditions or environment that may affect outcomes or decisions
The patient recovered quickly despite the adverse setting of the hospital ward during peak infection season.
O paciente se recuperou rapidamente apesar do ambiente adverso da enfermaria durante a época de pico de infecções.