1. In a manner showing diligent effort, attention, or hard work
He studied the subject with application and eventually mastered it.
Ele estudou o assunto com dedicação e eventualmente o dominou.
2. In a way that involves practical use or implementation
The new policy was implemented with application to all departments.
A nova política foi implementada com aplicação em todos os departamentos.
3. By means of putting something into practice or effect
Success comes with application of these proven strategies.
O sucesso vem com a aplicação dessas estratégias comprovadas.