open reading frame
[/ˈoʊpən ˈriːdɪŋ freɪm/]
nounpl: open reading frames
quadro de leitura aberta
1. A sequence of DNA or RNA that begins with a start codon and ends with a stop codon, potentially encoding a protein
The researchers identified a novel open reading frame in the viral genome that codes for an unknown protein.
Os pesquisadores identificaram um novo quadro de leitura aberta no genoma viral que codifica uma proteína desconhecida.
2. In molecular biology, a stretch of DNA/RNA with no stop codons in a particular reading frame, suggesting it may encode a functional protein
The software scans for open reading frames to predict potential genes in the sequenced DNA.
O software procura quadros de leitura aberta para prever genes potenciais no DNA sequenciado.
This is specialized scientific terminology used in molecular biology, genetics, and bioinformatics. The term is primarily found in academic and research contexts in both Brazil and Portugal. The acronym 'ORF' is universally recognized and used in scientific literature regardless of language or region.
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