mutated sequence

[ˈmjuːteɪtɪd ˈsiːkwəns]
nounpl: mutated sequences
sequência mutada
1. A DNA or RNA sequence that has undergone a permanent alteration in its nucleotide composition, resulting in a change from the original or wild-type sequence
The researchers identified a mutated sequence in the tumor cells that was responsible for the cancer's progression.
Os pesquisadores identificaram uma sequência mutada nas células tumorais que era responsável pela progressão do câncer.
2. A genetic code that differs from the original template due to insertions, deletions, substitutions, or other molecular changes
The mutated sequence showed a single nucleotide polymorphism that affected protein folding.
A sequência mutada mostrou um polimorfismo de nucleotídeo único que afetava o dobramento de proteínas.
This is primarily a scientific and medical term used in genetics research, molecular biology laboratories, and clinical settings in both Brazil and Portugal. It is fundamental to discussions of hereditary diseases, cancer biology, and evolutionary studies. The term has become increasingly important in Portuguese-speaking countries with the expansion of genomic research and personalized medicine initiatives.
Synonyms / Sinônimos
variant sequencealtered sequencemodified sequencemutant sequence
Antonyms / Antônimos
wild-type sequenceoriginal sequencenormal sequenceunmutated sequence

Regional Variations

General Brazilian Portuguese
sequência mutada
Standard term used in genetics and molecular biology contexts
São Paulo
sequência mutada
Commonly used in research institutions and medical genetics centers
Portugal
sequência mutada
Same usage as Brazilian Portuguese; standard scientific terminology
USA/Medical English
sequência genética alterada
Alternative formal translation emphasizing genetic alteration

Related Words

mutationDNAgenetic variationpolymorphismnucleotidegeneallele

Related Idioms & Phrases

point mutation
frameshift mutation
silent mutation
missense mutation
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