1. The quality of being malignant; extreme malevolence or harmfulness
The malignity of the disease made treatment difficult.
A malignidade da doença dificultou o tratamento.
2. Intense hatred or ill will; spiteful and venomous behavior
He acted with such malignity toward his former friend.
Ele agiu com tanta malignidade em relação ao seu antigo amigo.
3. Medical: the state of being malignant, especially in tumors or cancers
The malignity of the tumor required immediate surgical intervention.
A malignidade do tumor exigiu intervenção cirúrgica imediata.