1. A predetermined route or schedule of travel that has been fixed or determined in advance
The tour group followed the established itinerary throughout their week-long vacation.
O grupo de turismo seguiu o itinerário estabelecido durante suas férias de uma semana.
2. A planned sequence of stops, destinations, or activities that has been set according to specific requirements or preferences
The airline's established itinerary includes stopovers in three major cities.
O itinerário estabelecido da companhia aérea inclui paradas em três cidades principais.