1. A topic, issue, or subject of little importance or consequence
The argument was over an insignificant matter that could have been easily resolved.
A discussão era sobre um assunto insignificante que poderia ter sido facilmente resolvido.
2. Something trivial or unimportant in relation to larger concerns
In the grand scheme of things, his complaint was an insignificant matter.
No grande esquema das coisas, a sua reclamação era um assunto insignificante.