endothelial dysfunction
[en-doh-THEE-lee-ul dis-FUNK-shun]
nounfemininepl: disfunções endoteliais
disfunção endotelial
1. A pathological condition characterized by impaired function of the endothelium (the inner lining of blood vessels), leading to reduced production or availability of nitric oxide and increased vasoconstriction, inflammation, and thrombosis
Endothelial dysfunction is a key early step in the development of atherosclerosis and cardiovascular disease.
A disfunção endotelial é um passo inicial fundamental no desenvolvimento da aterosclerose e das doenças cardiovasculares.
2. A condition where blood vessels lose their ability to dilate properly in response to increased blood flow or physiological stimuli
Chronic hypertension contributes to endothelial dysfunction by damaging the inner lining of arteries.
A hipertensão crônica contribui para a disfunção endotelial ao danificar o revestimento interno das artérias.
This is a specialized medical and scientific term used in both English-speaking and Portuguese-speaking countries with identical technical meanings. It is primarily encountered in medical, pharmaceutical, and research contexts. In Brazil, the term is widely used in cardiology, internal medicine, and vascular surgery specialties. The condition has become increasingly important in preventive medicine discussions due to its role as an early indicator of cardiovascular disease risk, particularly in contexts involving lifestyle modification and risk factor management.
Related Idioms & Phrases
endothelial dysfunction and cardiovascular risk
markers of endothelial dysfunction
endothelial dysfunction-induced inflammation
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