cellular aggregation
[/ˈsɛljələr ˌæɡrɪˈɡeɪʃən/]
nounpl: cellular aggregations
agregação celular
1. The process or result of cells coming together and clustering to form a unified mass or tissue structure
Cellular aggregation is a critical process in embryonic development where individual cells group together to form organized tissues.
A agregação celular é um processo crítico no desenvolvimento embrionário onde células individuais se agrupam para formar tecidos organizados.
2. In microbiology, the clustering of microorganisms or bacteria into a cohesive mass
Biofilm formation involves cellular aggregation of bacteria that enables their survival in harsh environments.
A formação de biofilme envolve agregação celular de bactérias que permite sua sobrevivência em ambientes hostis.
3. The accumulation of cells in a specific location due to chemical or physical attraction
Cellular aggregation can be induced by specific signaling molecules that promote cell-to-cell adhesion.
A agregação celular pode ser induzida por moléculas sinalizadoras específicas que promovem adesão célula-a-célula.
This is primarily a scientific and medical term used in both Brazilian and American research contexts. It is not commonly used in everyday conversation. The term is essential in developmental biology, microbiology, and tissue engineering fields, with extensive research conducted in major American universities (MIT, Stanford, Harvard) and Brazilian institutions (USP, UFRJ, Fiocruz). The concept gained prominence in the late 20th century with advances in cellular biology and remains fundamental to understanding cancer metastasis and regenerative medicine.
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