cell line

[/sɛl laɪn/]
nounpl: cell lines
linhagem celular
1. A culture of cells derived from a single cell and therefore genetically identical, capable of dividing indefinitely in vitro
The HeLa cell line has been used in countless medical research studies since 1951.
A linhagem celular HeLa tem sido utilizada em inúmeros estudos de pesquisa médica desde 1951.
2. A homogeneous population of cells that originated from a single parent cell and maintain consistent characteristics through multiple passages
Researchers established a new cell line from the tumor tissue to study cancer progression.
Os pesquisadores estabeleceram uma nova linhagem celular a partir do tecido tumoral para estudar a progressão do câncer.
3. In biotechnology, cells that have been immortalized and can be cultured continuously for research purposes
The cell line showed remarkable stability even after 100 passages in culture.
A linhagem celular mostrou notável estabilidade mesmo após 100 passagens em cultura.
Cell line terminology is essential in modern biomedical research in both Brazil and the USA. The HeLa cell line, derived from African American woman Henrietta Lacks in 1951, represents a significant part of scientific history and has recently received increased cultural attention regarding ethics in medical research. In Brazil, as in the USA, cell line research is a cornerstone of pharmaceutical development, cancer research, and vaccine production, gaining particular prominence during discussions about COVID-19 vaccine development.
Synonyms / Sinônimos
cell straincultured cellscontinuous cultureimmortalized cells
Antonyms / Antônimos
primary cellsisolated cellsfresh tissue

Regional Variations

General Brazilian Portuguese
linhagem celular
Standard term used in academic and research contexts throughout Brazil
Portugal
linhagem celular
Same terminology used in Portuguese scientific and medical literature
São Paulo
linhagem celular
Common in major research institutions and universities
General English (USA)
cell line
Standard terminology in all American medical and biological research

Related Words

cell culturein vitropassageimmortalizationbiotechnologyviabilitycontamination

Related Idioms & Phrases

establish a cell line - criar uma linhagem celular
maintain a cell line - manter uma linhagem celular
passage of a cell line - passagem de uma linhagem celular
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