1. to cause someone to become hostile or opposed; to provoke or irritate
His rude comments antagonized the entire group.
Seus comentários rudes antagonizaram todo o grupo.
2. to act in opposition to; to oppose or work against
The new policy antagonizes environmental concerns.
A nova política antagoniza as preocupações ambientais.
3. in physiology, to act against the action of another muscle or substance
This muscle antagonizes the movement of the opposite limb.
Este músculo antagoniza o movimento do membro oposto.