alloimmunization
[/ˌæloʊˌɪmjənɪˈzeɪʃən/]
nounfemininepl: alloimmunizations / aloimunizações
aloimunização
1. The process by which an individual develops an immune response against antigens from another individual of the same species, typically through transfusion, transplantation, or pregnancy
Alloimmunization can occur in patients who receive multiple blood transfusions over time.
A aloimunização pode ocorrer em pacientes que recebem múltiplas transfusões de sangue ao longo do tempo.
2. The formation of antibodies against foreign tissue or blood antigens from a genetically different individual
The risk of alloimmunization increases with repeated exposure to incompatible blood products.
O risco de aloimunização aumenta com a exposição repetida a produtos sanguíneos incompatíveis.
3. In obstetrics, the sensitization of a pregnant woman to fetal antigens, particularly Rh antigen
Rh alloimmunization in pregnancy can lead to hemolytic disease of the newborn.
A aloimunização Rh na gravidez pode levar à doença hemolítica do recém-nascido.
Alloimmunization is primarily a medical and scientific term used in transfusion medicine, immunohematology, and obstetrics in both Brazil and the USA. It is particularly important in clinical settings regarding blood transfusions and pregnancy management. The term is standardized across English and Portuguese medical literature and carries no colloquial usage outside specialized medical contexts.
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