RNA microarray
[/ɑːr ɛn eɪ ˈmaɪkroʊəreɪ/]
nounpl: RNA microarrays
microarranjo de RNA
1. A laboratory tool used to detect the expression levels of thousands of genes simultaneously by measuring the amount of mRNA (messenger RNA) present in a biological sample
The researchers used an RNA microarray to analyze gene expression patterns in cancer cells.
Os pesquisadores utilizaram um microarranjo de RNA para analisar padrões de expressão gênica em células cancerosas.
2. A solid support (usually a glass slide or silicon chip) onto which thousands of DNA probes are attached in a grid pattern for hybridization with labeled RNA samples
The RNA microarray contained probes for over 20,000 different genes.
O microarranjo de RNA continha sondas para mais de 20.000 genes diferentes.
RNA microarray technology is fundamental in modern genomics and molecular biology research. The term is predominantly used in scientific and academic contexts in both Brazil and the United States. In Brazil, the Portuguese translation 'microarranjo de RNA' is preferred in formal scientific publications, though English terminology is widely understood in research institutions. This technology revolutionized gene expression analysis in the late 1990s and early 2000s before being partially superseded by RNA-seq technologies.
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