DNA microarray
[/ˈdiː.ɛn.ˈeɪ ˈmaɪ.kroʊ.əˌreɪ/]
nounpl: DNA microarrays
microarray de DNA
1. A laboratory tool used to detect the expression of thousands of genes simultaneously by analyzing the interaction between DNA samples and complementary DNA or RNA sequences attached to a solid support
Researchers used a DNA microarray to identify which genes were active in cancer cells.
Os pesquisadores usaram um microarray de DNA para identificar quais genes estavam ativos nas células cancerígenas.
2. A collection of microscopic spots of DNA sequences, called probes, arranged on a solid support such as a glass slide or silicon chip
The DNA microarray contained thousands of different probes for gene expression analysis.
O microarray de DNA continha milhares de diferentes sondas para análise de expressão gênica.
3. A technology platform used in genomics for high-throughput screening and analysis of genetic variations
DNA microarray analysis revealed significant mutations in the patient's genome.
A análise de microarray de DNA revelou mutações significativas no genoma do paciente.
DNA microarray technology represents a cornerstone of modern genomics research in both Brazil and the United States. This term is predominantly used in academic, research, and clinical laboratory settings. In Brazil, the technology is increasingly adopted by research institutions and universities for gene expression studies and personalized medicine applications. The term is typically used in its English form even in Portuguese-language scientific papers, though 'microarray de DNA' is the accepted Portuguese translation in formal contexts.
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