HDL degradation
[/eɪtʃ diː ɛl ˌdɛɡrəˈdeɪʃən/]
nounpl: HDL degradations
degradação de HDL
1. The biochemical process by which high-density lipoprotein (HDL) particles are broken down or reduced in concentration in the bloodstream, compromising their protective cardiovascular function
HDL degradation can increase cardiovascular disease risk by reducing the body's ability to remove excess cholesterol from arteries.
A degradação de HDL pode aumentar o risco de doença cardiovascular ao reduzir a capacidade do corpo de remover o excesso de colesterol das artérias.
2. The structural or functional impairment of HDL particles, reducing their effectiveness in reverse cholesterol transport
Oxidative stress can contribute to HDL degradation and loss of its cardioprotective properties.
O estresse oxidativo pode contribuir para a degradação de HDL e perda de suas propriedades cardioprotetoras.
HDL degradation is primarily a medical and scientific term used in both Brazilian and American healthcare contexts. It is particularly important in cardiology discussions as HDL cholesterol is considered 'good cholesterol' and its degradation is associated with increased cardiovascular risk. The term is used uniformly across Portuguese-speaking countries in medical literature and clinical settings.
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