1. in a contemptuous or mocking manner, expressing scorn or derision through facial expression or tone
He spoke with a sneer about her ambitions.
Ele falou com um sorriso de desprezo sobre suas ambições.
2. displaying disdain or mockery while making a statement or gesture
She replied with a sneer that left him speechless.
Ela respondeu com desprezo deixando-o sem palavras.