1. A path, road, or course of travel that is widely recognized and frequently used
The Appalachian Trail is a well-known route for hikers on the East Coast.
A Trilha dos Apalaches é uma rota bem conhecida para caminhantes na Costa Leste.
2. An established way of traveling between two points that many people are familiar with
This highway is a well-known route for commuters traveling to the city.
Esta rodovia é uma rota bem conhecida para os passageiros que viajam para a cidade.