1. A thorough and methodical examination or inquiry conducted according to an organized plan or procedure
The systematic investigation of the crime scene revealed crucial evidence.
A investigação sistemática da cena do crime revelou evidências cruciais.
2. A scientific or academic study carried out in an orderly, logical manner following established protocols
Researchers conducted a systematic investigation into the causes of the disease.
Os pesquisadores realizaram uma investigação sistemática sobre as causas da doença.