1. Large-scale, comprehensive, or radical alterations or modifications that affect many aspects or areas
The new CEO implemented sweeping changes to the company's organizational structure.
O novo CEO implementou mudanças drásticas na estrutura organizacional da empresa.
2. Far-reaching reforms or transformations that have wide-ranging consequences
The government announced sweeping changes to healthcare policy.
O governo anunciou mudanças drásticas na política de saúde.