1. A significant or meaningful addition, effort, or payment that has considerable impact or importance
Her research made a substantial contribution to the field of medicine.
Sua pesquisa fez uma contribuição substancial para o campo da medicina.
2. A considerable amount of money, resources, or work given to a cause, project, or organization
The company's substantial contribution to the charity helped thousands of families.
A contribuição substancial da empresa para a caridade ajudou milhares de famílias.
3. In legal or academic contexts, a noteworthy or material addition that significantly affects outcomes or conclusions
The witness provided a substantial contribution to the court case.
A testemunha forneceu uma contribuição substancial para o caso judicial.