1. A length of time that is notable, substantial, or long enough to be considered important or meaningful
The project took a significant duration to complete, lasting over two years.
O projeto levou uma duração significativa para ser concluído, durando mais de dois anos.
2. A period of time that has considerable importance or impact on a situation or outcome
After a significant duration of treatment, the patient showed improvement.
Após uma duração significativa de tratamento, o paciente mostrou melhora.