1. a substantial or considerable problem, obstacle, or challenge that is noteworthy and requires attention
The company faced significant difficulty in adapting to the new market regulations.
A empresa enfrentou dificuldade significativa em se adaptar aos novos regulamentos do mercado.
2. a serious impediment or barrier that meaningfully affects progress or success
He experienced significant difficulty learning the new software program.
Ele experimentou dificuldade significativa ao aprender o novo programa de software.