1. A response or answer that addresses the main point or core issue directly and comprehensively, rather than being evasive or superficial
The politician gave a substantive response to the journalist's question about the economy.
O político deu uma resposta substantiva à pergunta do jornalista sobre a economia.
2. In legal or formal contexts, a response that deals with the merits of a case or matter rather than procedural issues
The defendant's attorney filed a substantive response to the charges.
O advogado do réu apresentou uma resposta substantiva às acusações.
3. A meaningful, content-rich reply that provides substantial information or explanation
We need substantive responses from the committee, not just yes or no answers.
Precisamos de respostas substantivas da comissão, não apenas respostas sim ou não.