1. A geographic area that is remote, cut off, or separated from other populated areas, with limited access or connectivity
The mountain village is in an isolated region with no road access.
A aldeia na montanha fica em uma região isolada sem acesso por estrada.
2. An area experiencing social, economic, or political separation from mainstream society
The research team studied communities in isolated regions of the Amazon.
A equipe de pesquisa estudou comunidades em regiões isoladas da Amazônia.