reação em cadeia da polimerase
[ʁe.a.ˈsɐ̃w̃ ẽ ˈka.de.ja da po.li.me.ˈra.ze]
nounfemininepl: reações em cadeia da polimerase
polymerase chain reaction
1. A molecular biology technique used to amplify and simultaneously detect targeted DNA molecules based on the hybridization of oligonucleotides to a specific DNA sequence
The polymerase chain reaction has revolutionized genetic testing and forensic analysis.
A reação em cadeia da polimerase revolucionou os testes genéticos e a análise forense.
2. A process that uses repeated cycles of heating and cooling to denature DNA and allow for enzymatic replication
The PCR process requires a thermal cycler to maintain precise temperature changes.
O processo de reação em cadeia da polimerase exige um termociclador para manter mudanças de temperatura precisas.
3. A technique widely used in medical diagnostics, particularly for detecting viral infections such as COVID-19
COVID-19 tests often use PCR to detect viral RNA in patient samples.
Os testes de COVID-19 frequentemente usam reação em cadeia da polimerase para detectar RNA viral em amostras de pacientes.
PCR became a household term in Brazil and worldwide during the COVID-19 pandemic (2020-present), with 'teste de PCR' becoming commonly used in everyday language. The technique was developed by Kary Mullis in 1985 and earned him the Nobel Prize in Chemistry in 1993. In Brazilian healthcare and media, the abbreviation 'PCR' is typically used alongside the full Portuguese name, especially in medical reports and news coverage.
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