randomized control trial
[ˈrændəmaɪzd kənˈtroʊl ˈtraɪəl]
nounpl: randomized control trials
ensaio clínico randomizado
1. A research study in which participants are randomly assigned to either a treatment group or a control group to test the efficacy of an intervention, with the purpose of minimizing bias and establishing cause-and-effect relationships
The randomized control trial demonstrated that the new medication was significantly more effective than the placebo in reducing symptoms.
O ensaio clínico randomizado demonstrou que o novo medicamento era significativamente mais eficaz do que o placebo na redução dos sintomas.
2. The gold standard research design in clinical medicine and evidence-based practice for determining treatment effectiveness
Researchers conducted a large-scale randomized control trial to evaluate the safety and efficacy of the vaccine.
Os pesquisadores conduziram um ensaio clínico randomizado em larga escala para avaliar a segurança e eficácia da vacina.
Randomized control trials are considered the highest level of evidence in evidence-based medicine in both the USA and Brazil. In Brazil, the term is widely used in academic medical research and regulatory contexts by agencies like ANVISA (Agência Nacional de Vigilância Sanitária). The methodology is fundamental to drug approval processes and clinical research standards in both countries.
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