ortholog

[/ˈɔrθəlɔɡ/]
nounmasculinepl: orthologs
ortólogo
1. A gene or protein in different species that evolved from a common ancestral gene through speciation, typically retaining the same function
The hemoglobin gene in humans and chimpanzees are orthologs that share a common ancestor.
O gene da hemoglobina em humanos e chimpanzés são ortólogos que compartilham um ancestral comum.
2. In molecular biology, a sequence of DNA or protein that appears in different organisms and descended from the same sequence in their last common ancestor
Researchers identified orthologs of the insulin gene across multiple mammalian species.
Os pesquisadores identificaram ortólogos do gene da insulina em várias espécies de mamíferos.
This is a specialized term primarily used in scientific and academic contexts, particularly in molecular biology, bioinformatics, and evolutionary genetics. It is rarely used in casual conversation and is specific to discussions about genetic evolution and comparative genomics. The term is increasingly important in modern research, especially with the availability of complete genome sequences.
Synonyms / Sinônimos
homolog (in some contexts)orthologous geneorthologous sequence
Antonyms / Antônimos
paralogxenolog

Regional Variations

General Brazilian
ortólogo
Standard term used in genetics and molecular biology
Portugal
ortólogo
Same usage as Brazilian Portuguese in scientific contexts
Academic English
ortholog/orthologue
Both spellings accepted; 'ortholog' is more common in American English

Related Words

homologparalogsequence alignmentphylogeneticsspeciationsyntenymolecular evolution
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