1. To act against or resist the main goal or primary aim of a plan, organization, or initiative
The committee voted to oppose the principal objective of the merger proposal.
O comitê votou para opor-se ao objetivo principal da proposta de fusão.
2. To take a contrary position against the fundamental purpose or central intention
Several stakeholders decided to oppose the principal objective of the environmental reform.
Vários interessados decidiram opor-se ao objetivo principal da reforma ambiental.