1. The first location or venue where a tour, exhibition, show, or series of events begins
The opening destination for the world tour was Tokyo.
O destino de abertura da turnê mundial foi Tóquio.
2. In travel or tourism, the initial point of departure or first stop on an itinerary
Barcelona was chosen as the opening destination for the European cruise.
Barcelona foi escolhida como destino de abertura para o cruzeiro europeu.