1. A journey or voyage consisting of a single continuous leg or portion, without intermediate stops or transfers
The one-segment trip from New York to Los Angeles took five hours.
A viagem de um segmento de Nova York para Los Angeles levou cinco horas.
2. In airline or transportation terminology, a flight or route with no connecting flights or transfers
I prefer one-segment trips because they are more convenient than connecting flights.
Prefiro viagens de um segmento porque são mais convenientes que voos com conexão.