on-label use

[ɑn ˈleɪbəl ˈjuːs]
nounpl: on-label uses
uso conforme a bula
1. The use of a medication or medical device in accordance with the indications, dosages, and directions approved by regulatory authorities such as the FDA
The patient's treatment with the medication was an on-label use, as it was prescribed according to the FDA-approved indications.
O tratamento do paciente com o medicamento foi um uso conforme a bula, pois foi prescrito de acordo com as indicações aprovadas pela ANVISA.
2. Medical practice that follows the drug manufacturer's approved specifications and recommendations as stated in the prescribing information
Doctors prefer on-label use whenever possible to ensure patient safety and liability protection.
Os médicos preferem o uso conforme a bula sempre que possível para garantir a segurança do paciente e proteção de responsabilidade.
On-label use is a critical concept in pharmaceutical regulation and medical practice. In Brazil, the ANVISA (Agência Nacional de Vigilância Sanitária) oversees drug approval and labeling, similar to the FDA in the United States. Healthcare providers prioritize on-label use for legal protection and patient safety. Off-label use, while legal under certain circumstances in both countries, requires special documentation and informed consent. This terminology is essential in medical, pharmaceutical, and legal discussions.
Synonyms / Sinônimos
approved useauthorized uselabel-approved useFDA-approved use
Antonyms / Antônimos
off-label useunapproved usenon-labeled use

Regional Variations

General Brazilian Portuguese
uso conforme a bula
Most common translation in medical and pharmaceutical contexts
Brazil
uso autorizado
Alternative term emphasizing regulatory approval
Portugal
uso conforme o aprovado
Portuguese variant, sometimes uses 'uso aprovado'
United States
on-label use
Standard medical and legal terminology in the US healthcare system

Related Words

off-label useprescribing informationFDA approvalindicationpharmaceutical regulationdrug labeling

Related Idioms & Phrases

within the scope of the label
according to the prescribing information
as indicated on the package insert
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