1. A biochemical or physiological route or mechanism that is not specific to a particular substrate, receptor, or target; one that affects multiple pathways or systems indiscriminately
The drug acts through a non-selective pathway, affecting multiple cell receptors simultaneously.
O medicamento atua através de uma via não seletiva, afetando múltiplos receptores celulares simultaneamente.
2. In cell biology, a metabolic or signaling route that does not discriminate between different molecular targets
Non-selective pathway activation can lead to both therapeutic and adverse effects.
A ativação de uma via não seletiva pode levar tanto a efeitos terapêuticos quanto adversos.