non-randomized study
[nɑn-ˈræn.də.maɪzd ˈstʌd.i]
nounpl: non-randomized studies
estudo não randomizado
1. A clinical or observational research study in which participants are not assigned to treatment groups by random selection, but rather through deliberate allocation, convenience sampling, or observational methods
The non-randomized study showed a correlation between the new treatment and patient outcomes, but causation could not be definitively established.
O estudo não randomizado mostrou uma correlação entre o novo tratamento e os resultados dos pacientes, mas a causalidade não pôde ser estabelecida de forma definitiva.
2. A research design with lower internal validity compared to randomized controlled trials, as it cannot effectively control for confounding variables and selection bias
Because it was a non-randomized study, researchers acknowledged the limitations in drawing causal conclusions.
Por ser um estudo não randomizado, os pesquisadores reconheceram as limitações em tirar conclusões causais.
In academic and medical research contexts in both Brazil and Portugal, understanding the distinction between randomized and non-randomized studies is crucial for evaluating research quality. Non-randomized studies are often considered lower on the hierarchy of evidence but remain important for observational epidemiology and real-world effectiveness research. The terminology 'estudo não randomizado' is the standard in Brazilian medical literature, while Portuguese institutions may occasionally use 'estudo não aleatorizado,' though both terms are accepted.
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