nicotinic receptor
[/nɪkəˈtɪnɪk rɪˈsɛptər/]
nounmasculinepl: nicotinic receptors
receptor nicotínico
1. A type of ionotropic acetylcholine receptor that is activated by nicotine and other agonists, playing a crucial role in neuromuscular transmission and synaptic plasticity in the central and peripheral nervous systems
The nicotinic receptor is a ligand-gated ion channel that opens in response to acetylcholine binding.
O receptor nicotínico é um canal iônico ligado a ligante que se abre em resposta à ligação de acetilcolina.
2. A pentameric protein complex composed of five subunits arranged around a central ion channel pore, found primarily in neuronal synapses and the neuromuscular junction
Different combinations of nicotinic receptor subunits create receptors with distinct functional properties.
Diferentes combinações de subunidades de receptores nicotínicos criam receptores com propriedades funcionais distintas.
The term 'nicotinic receptor' is primarily used in scientific, medical, and academic contexts in both Brazil and the United States. It is not commonly used in everyday conversation. In Brazil, this terminology is standard in neuroscience research, pharmacology, and medical education. The discovery and characterization of nicotinic receptors has been fundamental to understanding neurobiology and has led to the development of medications for neurological disorders such as Alzheimer's disease and nicotine dependence treatment.
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