mitochondrial dysfunction
[maɪtoʊˈkɑːndriəl dɪsˈfʌŋkʃən]
nounfemininepl: disfunções mitocondriais
disfunção mitocondrial
1. A condition in which the mitochondria of cells fail to produce adequate energy (ATP), impairing normal cellular function and metabolism
Mitochondrial dysfunction has been linked to neurodegenerative diseases such as Parkinson's and Alzheimer's.
A disfunção mitocondrial tem sido associada a doenças neurodegenerativas como Parkinson e Alzheimer.
2. Impaired ability of mitochondria to generate energy efficiently, often resulting in fatigue, muscle weakness, and organ damage
Patients with mitochondrial dysfunction often experience chronic fatigue and cognitive impairment.
Pacientes com disfunção mitocondrial frequentemente experimentam fadiga crônica e comprometimento cognitivo.
3. A metabolic disorder characterized by defective oxidative phosphorylation in mitochondrial membrane structures
Research suggests that mitochondrial dysfunction may play a role in aging and age-related diseases.
Pesquisas sugerem que a disfunção mitocondrial pode desempenhar um papel no envelhecimento e doenças relacionadas à idade.
This is primarily a scientific and medical term used in both Brazil and the USA. In Brazil, it appears frequently in academic medical literature, research publications, and clinical settings. The term has gained prominence in recent years as mitochondrial research has expanded, particularly in studies of aging, chronic diseases, and rare genetic disorders. In the USA, it is commonly discussed in medical schools, research institutions, and among healthcare professionals dealing with metabolic and neurological conditions.
Related Idioms & Phrases
a mitochondria in distress
when the powerhouse fails
energia das células comprometida
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