macrodomain
[/ˌmækroʊˈdoʊmeɪn/]
nounmasculinepl: macrodomains
macrodomínio
1. A large, structurally distinct region or module within a protein or macromolecule, typically composed of multiple subdomains and functioning as an independent unit
The enzyme contains two macrodomains that work together to catalyze the reaction.
A enzima contém dois macrodomínios que trabalham juntos para catalisar a reação.
2. In virology, a conserved protein domain found in viral and cellular proteins involved in RNA recognition and processing
The macrodomain of this viral protein binds to ADP-ribose modifications on RNA.
O macrodomínio desta proteína viral se liga a modificações de ADP-ribose no RNA.
3. A large organizational unit or structural domain at the protein level in molecular biology
Researchers identified a novel macrodomain in the newly discovered protein complex.
Os pesquisadores identificaram um novo macrodomínio no complexo proteico recém-descoberto.
This is a specialized scientific term primarily used in molecular biology, structural biology, virology, and biochemistry research. It is equally understood and used in both Brazilian and European Portuguese scientific communities. The term does not have colloquial usage and is restricted to academic and professional scientific discourse.
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