leading strand

[/ˈliːdɪŋ strænd/]
nounpl: leading strands
fita líder
1. In molecular biology, the DNA strand that is synthesized continuously in the 5' to 3' direction during DNA replication, moving in the same direction as the replication fork
The leading strand is synthesized as a continuous strand of DNA, requiring only one RNA primer.
A fita líder é sintetizada como uma fita contínua de DNA, exigindo apenas um primer de RNA.
2. The strand of DNA that serves as the template for continuous synthesis during replication
DNA polymerase III synthesizes the leading strand continuously without interruption.
A DNA polimerase III sintetiza a fita líder continuamente sem interrupção.
This is a specialized scientific term used primarily in molecular biology, genetics, and biochemistry education and research. There are no significant cultural variations in usage between Brazil and the USA, as the terminology is standardized in scientific communities worldwide. Portuguese universities and research institutions use the same term as Brazilian institutions.
Synonyms / Sinônimos
continuous strandforward strand3' to 5' template strand
Antonyms / Antônimos
lagging stranddiscontinuous strand

Regional Variations

General Brazilian
fita líder
Standard term used in molecular biology courses and research
Portugal
fita líder
Same terminology as Brazil; may also be called 'cadeia contínua'
São Paulo
fita líder
Common in scientific and academic contexts

Related Words

lagging strandDNA replicationreplication forkOkazaki fragmentsDNA polymeraseprimer
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