1. Severe suffering, privation, or difficult circumstances that cause significant distress or struggle
The family endured great hardship during the economic crisis.
A família enfrentou grande dificuldade durante a crise econômica.
2. Extreme adversity or hardship that tests one's resilience and perseverance
Despite great hardship, she managed to complete her education.
Apesar da grande dificuldade, ela conseguiu completar seus estudos.