1. To complete or proceed with something that was planned or promised, despite difficulties or hesitation
She was nervous about the wedding, but she decided to go through with it.
Ela estava nervosa sobre o casamento, mas decidiu levar a cabo.
2. To persevere in doing something difficult or unpleasant until completion
He didn't want to attend the meeting, but he went through with it anyway.
Ele não queria ir à reunião, mas compareceu mesmo assim.